The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2006
Filed:
Dec. 19, 2003
Applicants:
Rudi Beyaert, Zingem, BE;
Ben Wielockx, Ghent, BE;
Sofie Van Huffel, Singapore, SG;
Filip Delaei, Reet, BE;
Claude Libert, Oudenaarde, BE;
Inventors:
Rudi Beyaert, Zingem, BE;
Ben Wielockx, Ghent, BE;
Sofie Van Huffel, Singapore, SG;
Filip Delaei, Reet, BE;
Claude Libert, Oudenaarde, BE;
Assignee:
Vlaams Interuniversitair Instituut Voor Biotechnologie VZW, Zwijnaarde, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the use of the A20-binding inhibitor of NF-κB activation (ABIN), or a functional fragment or variant thereof to protect against TNF-induced liver failure, such as viral hepatitis and alcoholic liver disease. More particularly, it relates to the prevention of the toxic effects of said diseases, including lethality, by overexpressing ABIN.