The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2006
Filed:
Sep. 25, 2002
Anand C. Burman, Ghaziabad, IN;
Sudhanand Prasad, Ghaziabad, IN;
Rama Mukherjee, Ghaziabad, IN;
Anu T. Singh, Ghaziabad, IN;
Archna Mathur, Ghaziabad, IN;
Neena Gupta, Ghaziabad, IN;
Anand C. Burman, Ghaziabad, IN;
Sudhanand Prasad, Ghaziabad, IN;
Rama Mukherjee, Ghaziabad, IN;
Anu T. Singh, Ghaziabad, IN;
Archna Mathur, Ghaziabad, IN;
Neena Gupta, Ghaziabad, IN;
Dabur Research Foundation, Ghaziabad, IN;
Abstract
The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing α, α-dialkylated amino acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptors on target cells. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.