The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7094559 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 22, 2006

Filed:

Aug. 08, 2001
Applicants:

Douglas C. Harnish, Warrington, PA (US);

Marshall S. Scicchitano, Douglasville, PA (US);

Sotirios K. Karathanasis, Saline, MI (US);

Chu-lai Hsiao, Waltham, MA (US);

Inventors:

Douglas C. Harnish, Warrington, PA (US);

Marshall S. Scicchitano, Douglasville, PA (US);

Sotirios K. Karathanasis, Saline, MI (US);

Chu-Lai Hsiao, Waltham, MA (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an assay system and method for testing compounds for their ability to regulate the hepatic lipase (HL) promoter. In particular, the invention relates to the identification of estrogen receptor ligands having this activity. Compounds that inhibit HL promoter activity are useful as leads, or on their own, to develop therapeutics in the prevention of heart disease.


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