The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7094538 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 22, 2006

Filed:

Jun. 10, 2002
Applicants:

Eldon R. Jupe, Norman, OK (US);

Linda F. Thompson, Oklahoma City, OK (US);

Regina Resta, Slingersland, NY (US);

Robert T. Dell'orco, Gaithersburg, MD (US);

Inventors:

Eldon R. Jupe, Norman, OK (US);

Linda F. Thompson, Oklahoma City, OK (US);

Regina Resta, Slingersland, NY (US);

Robert T. Dell'Orco, Gaithersburg, MD (US);

Assignee:

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The lifetime probability of a person developing cancer can now be determined based on an allelic variation found in the 3'UTR of the prohibitin gene. The probability is dependent on the sequence of the 3′UTR at position 729, i.e., whether there is a thymine (T) or a cytosine (C) or both at this position. Determining the sequence at the position 729 can be done by any number of standard techniques. Preferably, the sequence is determined by amplifying this region by PCR and subjecting it to an RFLP analysis.


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