The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2006
Filed:
Nov. 22, 2001
Kenji Yasuda, Tokyo, JP;
Kunihiko Kaneko, Kanagawa, JP;
Tetsuya Yomo, Osaka, JP;
Ippei Inoue, Saitama, JP;
Yuichi Wakamoto, Tokyo, JP;
Kenji Yasuda, Tokyo, JP;
Kunihiko Kaneko, Kanagawa, JP;
Tetsuya Yomo, Osaka, JP;
Ippei Inoue, Saitama, JP;
Yuichi Wakamoto, Tokyo, JP;
Japan Science and Technology Corporation, Saitama, JP;
Abstract
An apparatus is provided with a cell culture container having a cell culture region made of a hole formed on a substrate, a semi-permeable membrane covering a top plane of the cell culture region and a culture medium replacement part provided over the semi-permeable membrane, a mechanism for supplying a cell culture medium into the cell culture container, and a microscopic optical mechanism for enabling long-term observation of the cell within the cell culture region. This apparatus makes it possible to culture a cell group originating from a particular single cell, to perform culture and observation while identifying cells to be subjected to interaction during the process of culturing cells, and observe a difference in variation between the particular cell and other cells. There is also provided a mechanism which makes it possible to collect only a cell assuming a particular state and perform analysis or biochemical measurement of a gene of the cell, an expressed mRNA and the like.