The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2006
Filed:
Feb. 18, 2004
Applicants:
Gregg Brian Feigelson, Chester, NY (US);
Joseph Zeldis, New City, NY (US);
Ivo Ladislav Jirkovsky, Waitsfield, VT (US);
Inventors:
Gregg Brian Feigelson, Chester, NY (US);
Joseph Zeldis, New City, NY (US);
Ivo Ladislav Jirkovsky, Waitsfield, VT (US);
Assignee:
Wyeth, Madison, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for formation of N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane side-chains having the structure shown in formula below, and for making intermediate compounds therefor. In this process, chirality is introduced at the piperazine ring formation step and 2-aminopyridyl substitution is incorporated via displacement. The resulting N, N′ disubstituted piperazines act on the central nervous system at 5HT receptors.