The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2006

Filed:

Oct. 30, 2003
Applicants:

Jianping Cai, West Caldwell, NJ (US);

Nikolaos Dimoudis, Wielenbach, DE;

Konrad Honold, Penzberg, DE;

Kin-chun Luk, North Caldwell, NJ (US);

Stefan Scheiblich, Penzberg, DE;

Hilke Sudergat, Munich, DE;

Georg Tiefenthaler, Sindelsdorf, DE;

Oliver Tonn, Penzberg, DE;

Inventors:

Jianping Cai, West Caldwell, NJ (US);

Nikolaos Dimoudis, Wielenbach, DE;

Konrad Honold, Penzberg, DE;

Kin-Chun Luk, North Caldwell, NJ (US);

Stefan Scheiblich, Penzberg, DE;

Hilke Sudergat, Munich, DE;

Georg Tiefenthaler, Sindelsdorf, DE;

Oliver Tonn, Penzberg, DE;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 491/113 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula I are described. These compounds are protein kinase inhibitors, in particular they inhibit the src family tyrosine kinases. Thus, these compounds are useful for the treatment of diseases mediated by src tyrosine kinases, including cell proliferative disorders such as cancer. Also described are methods of making and using compounds of formula I as well as pharmaceutical compositions containing these compounds.


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