The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2006

Filed:

Dec. 30, 2003
Applicants:

Heinz Redl, Vienna, AT;

Walter Fuerst, Vienna, AT;

Rudolf Kneidinger, Vienna, AT;

Sam L. Helgerson, Altadena, CA (US);

Douglas Looker, Ft. Lupton, CO (US);

Elisabeth M. Inman, Pasadena, CA (US);

Jane P. Richards, Longmont, CO (US);

Catalina Wong, Los Angeles, CA (US);

Inventors:

Heinz Redl, Vienna, AT;

Walter Fuerst, Vienna, AT;

Rudolf Kneidinger, Vienna, AT;

Sam L. Helgerson, Altadena, CA (US);

Douglas Looker, Ft. Lupton, CO (US);

Elisabeth M. Inman, Pasadena, CA (US);

Jane P. Richards, Longmont, CO (US);

Catalina Wong, Los Angeles, CA (US);

Assignees:

Baxter Aktiengesellschaft, Vienna, AU;

Baxter International Inc., Deerfield, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7088 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); C07H 21/00 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
Abstract

A fibrin/fibrinogen binding conjugate for forming a depot for the sustained release of a pharmaceutically active substance from a fibrin clot. The conjugate comprises a fibrin/fibrinogen binding moiety bound to a pharmaceutically active substance either directly or via an intervening substance capturing moiety such as an antibody. The conjugate can also be a recombinant fusion protein comprising a fibrin/fibrinogen binding moiety such as VEGFC-terminal domain fused to a wound-healing substance such as leptin.


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