The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2006

Filed:

Jul. 11, 2001
Applicants:

Cristina Gardelli, Rome, IT;

Claudio Giuliano, Rome, IT;

Steven Harper, Rome, IT;

Uwe Koch, Rome, IT;

Frank Narjes, Rome, IT;

Jesus Maria Ontoria Ontoria, Rome, IT;

Marco Poma, Rome, IT;

Simona Ponzi, Rome, IT;

Ian Stansfield, Rome, IT;

Vincenzo Summa, Rome, IT;

Inventors:

Cristina Gardelli, Rome, IT;

Claudio Giuliano, Rome, IT;

Steven Harper, Rome, IT;

Uwe Koch, Rome, IT;

Frank Narjes, Rome, IT;

Jesus Maria Ontoria Ontoria, Rome, IT;

Marco Poma, Rome, IT;

Simona Ponzi, Rome, IT;

Ian Stansfield, Rome, IT;

Vincenzo Summa, Rome, IT;

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/557 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 417/14 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A class of 2-aryl-4,5-dihydroxy-6-carboxypyrimidines of formula (I): wherein Ar is an optionally substituted aryl or heterocyclicgroup; as well as compounds of formula (I) which are derivatized at one or more of the 4-hydroxy, 5-hydroxy or 6-carboxy groups; and tautomers thereof, and pharmaceutically acceptable salts or esters thereof; and inhibitors of viral polymerases, especially the hepatitis C virus (HCV) polymerase enzyme


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