The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2006
Filed:
Mar. 03, 2004
Shinn Chih Wu, Miaoli, TW;
Teng Kuei Cheng, Taipei, TW;
Chuan Mu Chen, Taichung, TW;
Shau Ping Lin, Taipei, TW;
Chon Ho Yen, Taichung, TW;
Ping Cheng Yang, Hsinchu, TW;
Shinn Chih Wu, Miaoli, TW;
Teng Kuei Cheng, Taipei, TW;
Chuan Mu Chen, Taichung, TW;
Shau Ping Lin, Taipei, TW;
Chon Ho Yen, Taichung, TW;
Ping Cheng Yang, Hsinchu, TW;
Animal Technology Institute Taiwan, Miaoli, TW;
Abstract
The present invention discloses a method for expressing multiple recombinant proteins in transgenic non-human mammalian milk, characterized in which human clotting factor IX gene and porcine lactoferrin gene are transferred into the mammal by gene injection and embryonic implantation to obtain expression in the milk of transgenic mammal and its filial generation. The method of this invention can maintain the stable expression of multiple recombinant proteins in the transgenic mammal during lactation and stable expression amount proximate to that of the first generation in the offsprings of the transgenic non-human mammal.