The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2006

Filed:

Nov. 18, 2004
Applicants:

Timothy Norris, Gales Ferry, CT (US);

Jeffrey W. Raggon, North Stonington, CT (US);

Richard D. Connell, East Lyme, CT (US);

James D. Moyer, East Lyme, CT (US);

Michael J. Morin, Waterford, CT (US);

Shama M. Kajiji, Mystic, CT (US);

Barbara A. Foster, Mystic, CT (US);

Karen J. Ferrante, East Greenwich, RI (US);

Sandra L. Silberman, Randolph, NJ (US);

Inventors:

Timothy Norris, Gales Ferry, CT (US);

Jeffrey W. Raggon, North Stonington, CT (US);

Richard D. Connell, East Lyme, CT (US);

James D. Moyer, East Lyme, CT (US);

Michael J. Morin, Waterford, CT (US);

Shama M. Kajiji, Mystic, CT (US);

Barbara A. Foster, Mystic, CT (US);

Karen J. Ferrante, East Greenwich, RI (US);

Sandra L. Silberman, Randolph, NJ (US);

Assignee:

OSI Pharmaceuticals, Inc., Melville, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07D 239/84 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of monotherapy for a subject suffering from abnormal cell growth expressing the epidermal growth factor receptor (EGFR) which comprises orally administering to the subject a therapeutically effective amount of a crystalline polymorph of the hydrochloride salt of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine so as to treat the subject.


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