The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2006

Filed:

Jan. 03, 2001
Applicants:

Robert Charles Atkins, Canterbury, Victoria 3126, AU;

Steven James Chadban, Blackrock, Victoria 3193, AU;

Mark Emmanuel Cooper, East Prahran, Victoria 3181, AU;

Richard Ernest Gilbert, West St. Kilda, Victoria 3182, AU;

Prudence Ann Hill, Canterbury, Victoria 3126, AU;

Darren James Kelly, Chirnside Village, Victoria 3116, AU;

David John Nikolic-paterson, Pearcedale, Victoria 3912, AU;

Inventors:

Robert Charles Atkins, Canterbury, Victoria 3126, AU;

Steven James Chadban, Blackrock, Victoria 3193, AU;

Mark Emmanuel Cooper, East Prahran, Victoria 3181, AU;

Richard Ernest Gilbert, West St. Kilda, Victoria 3182, AU;

Prudence Ann Hill, Canterbury, Victoria 3126, AU;

Darren James Kelly, Chirnside Village, Victoria 3116, AU;

David John Nikolic-Paterson, Pearcedale, Victoria 3912, AU;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the use of PDGF receptor tyrosine kinase inhibitors, especially of N-phenyl-2-pyrim-idine-amine derivatives of formula (I), in which the symbols and substituents have the meaning as defined herein in free form or in pharmaceutically acceptable salt form, in the manufacture of a pharmaceutical composition for the treatment of diabetic nephropathy; to a method of treatment of warm-blooded animals, including humans, suffering from diabetic nephropathy; and to the use of a PDGF receptor tyrosine kinase inhibitor of the formula (I), wherein Ris pyridyl bonded at a carbon atom, R, R, R, Rand Rare each hydrogen, Ris lower alkyl, Ra radical of formula (II): —N(R)—C(═X)—(Y)—R, wherein Rhydrogen, X is oxo, n is 0 and Ris 4-methyl-piperazinyl-methyl, or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for treating glomerulonephritis, chronic pyelonephritis or IgA nephropathy.


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