The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2006
Filed:
Feb. 23, 2005
Hyun K. Kim, Bethesda, MD (US);
Richard P. Blye, Highland, MD (US);
Pemmaraju N. Rao, San Antonio, TX (US);
James W. Cessac, San Antonio, TX (US);
Carmie K. Acosta, San Antonio, TX (US);
Hyun K. Kim, Bethesda, MD (US);
Richard P. Blye, Highland, MD (US);
Pemmaraju N. Rao, San Antonio, TX (US);
James W. Cessac, San Antonio, TX (US);
Carmie K. Acosta, San Antonio, TX (US);
Abstract
A compound having the general formula: in which: Ris a member selected from the group consisting of —OCH, —SCH, —N(CH), —NHCH, —CHO, —COCHand —CHOHCH; Ris a member selected from the group consisting of halogen, alkyl, acyl, hydroxy, alkoxy, acyloxy, alkyl carbonate, cypionyloxy, S-alkyl and S-acyl; Ris a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; Ris a member selected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of ═O and ═N—OR, wherein Ris a member selected from the group consisting of hydrogen and alkyl. In addition to providing the compounds of Formula I, the present invention provides methods wherein the compounds of Formula I are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce labor; and for contraception.