The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2006

Filed:

Jan. 12, 2001
Applicants:

Kenneth A. Jacobson, Silver Spring, MD (US);

Victor E. Marquez, Montgomery Village, MD (US);

Inventors:

Kenneth A. Jacobson, Silver Spring, MD (US);

Victor E. Marquez, Montgomery Village, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/16 (2006.01); C07D 473/18 (2006.01); C07D 473/34 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel nucleoside and nucleotide derivatives that are useful agonists or antagonists of P1 or P2 receptors. For example, the present invention provides a compound of formula A-M, wherein A is modified adenine or uracil and M is a constrained cycloalkyl group. The adenine or uracil is bonded to the constrained cycloakyl group. The compounds of the present invention are useful in the treatment or prevention of various diseases including airway diseases (through A, A, P2Yreceptors), cancer (through A, P2 receptors), cardiac arrhythmias (through Areceptors), cardiac ischemia (through A, Areceptors), epilepsy (through A, P2X receptors), and Huntington's Disease (through Areceptors).


Find Patent Forward Citations

Jacobson, Kenneth. (2006). Methanocarba cycloakyl nucleoside analogues (U.S. Patent No. 7087589). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7087589

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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