The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2006
Filed:
Feb. 21, 2003
Paul Armstrong, Edmonton, CA;
Hal Barron, San Francisco, CA (US);
Silvano Berioli, Perugia, IT;
Frederique Bigonzi, 1'Hay les Roses, FR;
Erich Bluhmki, Schwendi, DE;
Richard Chin, San Francisco, CA (US);
Christopher Granger, Durham, NC (US);
Frans Van DE Werf, Herent, BE;
Fong Wang-clow, Los Altos Hills, CA (US);
Paul Armstrong, Edmonton, CA;
Hal Barron, San Francisco, CA (US);
Silvano Berioli, Perugia, IT;
Frederique Bigonzi, 1'Hay les Roses, FR;
Erich Bluhmki, Schwendi, DE;
Richard Chin, San Francisco, CA (US);
Christopher Granger, Durham, NC (US);
Frans Van De Werf, Herent, BE;
Fong Wang-Clow, Los Altos Hills, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Aventis Pharma, S.A., Antony, FR;
Boehringer Ingelheim Pharma KG, Ingelheim/Rhein, DE;
Abstract
The invention concerns an improved therapeutic regimen for the treatment of thrombolytic disorders, such as acute myocardial infarction (AMI). In particular, the present invention concerns the treatment of thrombolytic disorders, e.g. AMI, with a combination of a tissue plasminogen activator (t-PA) variant having improved fibrin specificity and extended plasma half-life when compared with wild-type human t-PA and a low molecular weight heparin.