The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2006

Filed:

Jul. 04, 1997
Applicants:

David Philip Lane, Fife, GB;

Volker Böttger, Germering-Unterpfaffenhofen, DE;

Angelika Böttger, Germering-Unterpfaffenhofen, DE;

Steven Michael Picksley, Bradford, GB;

Heinz-kurt Hochkeppel, Aesch, CH;

Carlos Garcia-echeverria, Basel, CH;

Patrick Chène, Mulhouse, FR;

Pascal Furet, Thann, FR;

Inventors:

David Philip Lane, Fife, GB;

Volker Böttger, Germering-Unterpfaffenhofen, DE;

Angelika Böttger, Germering-Unterpfaffenhofen, DE;

Steven Michael Picksley, Bradford, GB;

Heinz-Kurt Hochkeppel, Aesch, CH;

Carlos Garcia-Echeverria, Basel, CH;

Patrick Chène, Mulhouse, FR;

Pascal Furet, Thann, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 38/12 (2006.01); A61K 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounds, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild type p53 suppressor by interfering with the interaction between human p53 and human MDM2.


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