The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2006

Filed:

Feb. 11, 2003
Applicants:

Subramanian Iyer, Hockessin, DE (US);

William L. Johnson, Wilmington, DE (US);

Lance Nguyen, Telford, PA (US);

Steven C. Ross, Wilmington, DE (US);

Ruye Xing, Avondale, PA (US);

Inventors:

Subramanian Iyer, Hockessin, DE (US);

William L. Johnson, Wilmington, DE (US);

Lance Nguyen, Telford, PA (US);

Steven C. Ross, Wilmington, DE (US);

Ruye Xing, Avondale, PA (US);

Assignee:

Arkion Life Sciences, LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a composition comprising a substantially purified Cytokine Inhibitory Factor (CIF) having certain characteristics, including the ability to inhibit RNA transcription of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF-α), interleukin-1-beta (IL-1β), and interleukin-2 (IL-2). Also disclosed is a method for substantially purifying the Cytokine Inhibitory Factor and a method for modulating the immune system of an animal using such composition.


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