The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2006

Filed:

Mar. 12, 2003
Applicants:

Michel Schneider, Troinex, CH;

Feng Yan, Carouge, CH;

Nadine Garcel, Legal Representative, Ambilly, FR;

Jerome Puginier, Le Chable-Beaumont, FR;

Marie-bernadette Barrau, Genéve, CH;

Philippe Bussat, Feigeres, FR;

Eva Hybl, Heidelberg, DE;

Daniel Bichon, Montpellier, FR;

Inventors:

Michel Schneider, Troinex, CH;

Feng Yan, Carouge, CH;

Nadine Garcel, legal representative, Ambilly, FR;

Jerome Puginier, Le Chable-Beaumont, FR;

Marie-Bernadette Barrau, Genéve, CH;

Philippe Bussat, Feigeres, FR;

Eva Hybl, Heidelberg, DE;

Daniel Bichon, Montpellier, FR;

Assignee:

Bracco International B.V., Amsterdam, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A18B 8/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain surfactants and, optionally, hydrophilic stabilizers. The surfactants can be in the form of liposomes. The suspensions are obtained by exposing the surfactants to air or a gas before or after admixing with an aqueous phase. One can impart outstanding resistance against collapse under pressure to these gas-filled microbubbles used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditions, divided by the square root of the molecular weight does not exceed 0.003. Contrast agents with particular mixtures of gases are also disclosed that have advantageous properties.


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