The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2006
Filed:
Nov. 17, 2003
Applicants:
Hyun-ik Shin, Daejeon, KR;
Bo-seung Choi, Daejeon, KR;
Inventors:
Hyun-Ik Shin, Daejeon, KR;
Bo-Seung Choi, Daejeon, KR;
Assignee:
LG Life Sciences Ltd., Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/173 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is related to a novel process for preparing an optically active 5-hydroxy-3-oxo-hexanoic acid derivative or its tautomer which is useful intermediate for preparing statins such as atorvastatin and rosuvastatin. Blaise reaction of (S)-4-halo-3-hydroxybutyronitrile with -haloacetate is utilized as a key reaction to provide the product with minimal formation of side products and in good yield.