The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2006

Filed:

Nov. 28, 2000
Applicants:

Michael Barry Gravestock, Waltham, MA (US);

Michael John Betts, Macclesfield, GB;

Inventors:

Michael Barry Gravestock, Waltham, MA (US);

Michael John Betts, Macclesfield, GB;

Assignee:

AstraZeneca AB, Södertälje, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/42 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein, for example, X is O, S or NH; HET is an optionally substituted C-linked 5-membered heteroaryl ring containing 2 to 4 heteroatoms independently selected from N, O and S; Q is selected from, for example, Q1 and Q2: Rand Rare independently hydrogen or fluoro; T is selected from a range of groups, for example, an N-linked (fully unsaturated) 5-membered heteroaryl ring system or a group of formula (TC5): wherein Rc is, for example, RCO—, RSO— or RCS—; wherein Ris, for example, optionally substituted (1–10C)alkyl or RC(O)O(1–6C)alkyl wherein Ris optionally substituted (1–10C)alkyl; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described


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