The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2006

Filed:

Feb. 26, 2004
Applicant:

Leyi Gong, San Mateo, CA (US);

Inventor:

Leyi Gong, San Mateo, CA (US);

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01); C07D 451/04 (2006.01); C07D 487/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having the formula (I),Ar—(F)-(E)-(CRR)—(CHR)-(T)-(Q)-Ar,are useful as CCR-3 receptor antagonists, wherein T is a bridged heterocyclyl group having one N atom and a bridge of one to two bridgehead carbon atoms; Ar and Arare aryl or heteroaryl; F is alkylene, alkenylene, or a bond; E is —C(═O)N(R)—, —SON(R)—, —N(R)C(═O)N(R)—, —N(R)SON(R)—, —N(R)C(═S)N(R)—, —N(R)C(═O)—, —N(R)SO—, —N(R)C(═O)CH(R)—, or CH(R)C(═O)N(R)—; Q is —C(═O)— or Calkylene; and R, R, R, R, R, R, R, and Rare defined as set forth in the specification.


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