The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2006

Filed:

May. 04, 2005
Applicants:

Chen Chen, San Diego, CA (US);

Dongpei Wu, San Diego, CA (US);

Zhiqiang Guo, San Diego, CA (US);

Martin Rowbottom, San Diego, CA (US);

Inventors:

Chen Chen, San Diego, CA (US);

Dongpei Wu, San Diego, CA (US);

Zhiqiang Guo, San Diego, CA (US);

Martin Rowbottom, San Diego, CA (US);

Assignee:

Neurocrine Biosciences, Inc., San Diego, CA (US);

Attorney:
Int. Cl.
CPC ...
C07D 211/14 (2006.01); C07D 213/63 (2006.01); C07D 237/14 (2006.01); A61K 31/44 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R, R, R, R, R, R, R, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.


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