The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2006
Filed:
Apr. 11, 2005
Alan J. Hutchison, Madison, CT (US);
John M. Peterson, Durham, CT (US);
Dario Doller, Wallingford, CT (US);
Wallace C. Pringle, Guilford, CT (US);
Helen Yin, Milford, CT (US);
Alan J. Hutchison, Madison, CT (US);
John M. Peterson, Durham, CT (US);
Dario Doller, Wallingford, CT (US);
Wallace C. Pringle, Guilford, CT (US);
Helen Yin, Milford, CT (US);
Neurogen Corp., Branford, CT (US);
Abstract
Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).