The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2006

Filed:

Nov. 21, 2003
Applicants:

Ian Richard Matthews, Oxfordshire, GB;

Thomas Stephen Coulter, Oxfordshire, GB;

Chiara Ghiron, Oxfordshire, GB;

Chris James Brennan, Oxfordshire, GB;

Muhammed Kamal Uddin, Oxfordshire, GB;

Lars Olof Göran Pettersson, Lund, SE;

Dorthe Da Graca Thrige, Lund, SE;

Philip Huxley, Oxfordshire, GB;

Inventors:

Ian Richard Matthews, Oxfordshire, GB;

Thomas Stephen Coulter, Oxfordshire, GB;

Chiara Ghiron, Oxfordshire, GB;

Chris James Brennan, Oxfordshire, GB;

Muhammed Kamal Uddin, Oxfordshire, GB;

Lars Olof Göran Pettersson, Lund, SE;

Dorthe da Graca Thrige, Lund, SE;

Philip Huxley, Oxfordshire, GB;

Assignee:

Active Biotech AB, Lund, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); C07D 495/06 (2006.01); A61K 31/437 (2006.01); A61K 31/4162 (2006.01); A61P 37/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.


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