The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2006
Filed:
Jun. 17, 2002
Ryuji Kubota, Tokyo, JP;
Hiroshi Araya, Gotenba, JP;
Kouki Obata, Gotenba, JP;
Nobuyuki Kimura, Sakura, JP;
Hiroyuki Fukui, Chiba, JP;
Hidetsugu Takagaki, Sakura, JP;
Ryuji Kubota, Tokyo, JP;
Hiroshi Araya, Gotenba, JP;
Kouki Obata, Gotenba, JP;
Nobuyuki Kimura, Sakura, JP;
Hiroyuki Fukui, Chiba, JP;
Hidetsugu Takagaki, Sakura, JP;
Dainippon Ink and Chemicals, Inc., Tokyo, JP;
Abstract
A quinolinone derivative pharmaceutical composition comprising a quinolinone derivative represented by the structural formula (I): wherein the quinolinone derivative is in the form of particles, which have an average particle diameter of 0.5 to 10 μm and such a particle size distribution that particles having a particle diameter of 15 μm or less account for 90% or more of the totality of the particles, and also have a fusion enthalpy of 30 J/g or more, and the surface of the particles are coated with a water-soluble composition containing a water-soluble polymer, can quickly dissolve an active ingredient in the digestive tract and is also superior in long-term storage stability.