The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2006

Filed:

Jun. 04, 1997
Applicants:

Carl T. Wittwer, Salt Lake City, UT (US);

Kirk M. Ririe, Idaho Falls, ID (US);

Randy P. Rasmussen, Salt Lake City, UT (US);

David R. Hillyard, Salt Lake City, UT (US);

Inventors:

Carl T. Wittwer, Salt Lake City, UT (US);

Kirk M. Ririe, Idaho Falls, ID (US);

Randy P. Rasmussen, Salt Lake City, UT (US);

David R. Hillyard, Salt Lake City, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such as the DNA polymerase chain reaction. Biological samples are placed in glass micro capillary tubes and then located inside the sample chamber. A programmable controller regulates the temperature of the sample inside the sample chamber. Monitoring of the DNA amplification is monitored by fluorescence once per cycle or many times per cycle. The present invention provides that fluorescence monitoring of PCR is a powerful tool for DNA quantification.


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