The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2006

Filed:

Apr. 08, 2004
Applicant:

Eberhard Amtmann, Heidelberg, DE;

Inventor:

Eberhard Amtmann, Heidelberg, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 279/02 (2006.01); A61K 31/155 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to salts of guanidine derivatives of formula R—X—C(═NH)NHZ, wherein X represents a valence bond, —CH—NH—, —CH—NH—NH— or —CH═N—NH—; R represents a linear or branched C–Calkyl, C–Ccycloalkyl, adamantyl, norbornyl, tricyclodecyl, benzyl, furyl, pyridyl, anthracyl, naphthyl, phenanthryl, perinaphthyl or quinuclidinyl residue, which can be substituted by one or more hydroxyl groups, C–Calkoxy groups, C–Calkyl groups and/or one or more halogen atoms or one or more amino groups; Z represents O—CO—Y, O—S(O)—Y, or O—P(O)(OH)—Y; and Y represents a linear or branched C–Calkyl, C–Ccycloalkyl, benzyl, furyl or pyridyl residue, which can be substituted by one or more hydroxyl groups, carboxylic acid groups, C–Calkoxy groups, C–Calkyl groups and/or one or more halogen atoms or one or more amino groups. These compounds are useful for treating tumor diseases, autoimmune diseases, cardiovascular diseases, infections, and viral diseases.


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