Salts of guanidine derivatives and pharmaceutical preparations consisting thereof

Abstract

This invention relates to salts of guanidine derivatives of formula R—X—C(═NH)NHZ, wherein X represents a valence bond, —CH—NH—, —CH—NH—NH— or —CH═N—NH—; R represents a linear or branched C–Calkyl, C–Ccycloalkyl, adamantyl, norbornyl, tricyclodecyl, benzyl, furyl, pyridyl, anthracyl, naphthyl, phenanthryl, perinaphthyl or quinuclidinyl residue, which can be substituted by one or more hydroxyl groups, C–Calkoxy groups, C–Calkyl groups and/or one or more halogen atoms or one or more amino groups; Z represents O—CO—Y, O—S(O)—Y, or O—P(O)(OH)—Y; and Y represents a linear or branched C–Calkyl, C–Ccycloalkyl, benzyl, furyl or pyridyl residue, which can be substituted by one or more hydroxyl groups, carboxylic acid groups, C–Calkoxy groups, C–Calkyl groups and/or one or more halogen atoms or one or more amino groups. These compounds are useful for treating tumor diseases, autoimmune diseases, cardiovascular diseases, infections, and viral diseases.