The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2006
Filed:
Jan. 31, 2003
Applicants:
Christopher J. Corcoran, Arlington, MA (US);
Michael J. Agostino, Andover, MA (US);
Edward R. Lavallie, Harvard, MA (US);
Carl R. Flannery, Acton, MA (US);
Lisa A. Collins-racie, Acton, MA (US);
Inventors:
Christopher J. Corcoran, Arlington, MA (US);
Michael J. Agostino, Andover, MA (US);
Edward R. LaVallie, Harvard, MA (US);
Carl R. Flannery, Acton, MA (US);
Lisa A. Collins-Racie, Acton, MA (US);
Assignee:
Wyeth, Madison, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); C12N 1/21 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.