The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2006
Filed:
Dec. 21, 1999
Tracy Ann Willson, North Balwyn, AU;
Richard John Simpson, Richmond, AU;
Alison Mary Farley, Port Fairy, AU;
Sandra Elaine Nicholson, Newport, AU;
Jian-guo Zhang, North Melbourne, AU;
Manuel Baca, Ivanhoe, AU;
Nicos A. Nicola, Mont Albert, AU;
Douglas J. Hilton, Warrandyte, AU;
Warren Scott Alexander, Moonee Ponds, AU;
Donald Metcalf, Balwyn, AU;
Tracy Ann Willson, North Balwyn, AU;
Richard John Simpson, Richmond, AU;
Alison Mary Farley, Port Fairy, AU;
Sandra Elaine Nicholson, Newport, AU;
Jian-Guo Zhang, North Melbourne, AU;
Manuel Baca, Ivanhoe, AU;
Nicos A. Nicola, Mont Albert, AU;
Douglas J. Hilton, Warrandyte, AU;
Warren Scott Alexander, Moonee Ponds, AU;
Donald Metcalf, Balwyn, AU;
The Walter & Eliza Hall Institute of Medical Research, Victoria, AU;
Abstract
The present invention relates generally to amino acid sequences obtainable from SOCS proteins and which are capable of interacting with intracellular molecules. The present invention further relates to nucleic acid molecules encoding said amino acid sequences. The amino acid sequences and the nucleic acid molecules encoding same of the present invention are useful in modulating degradation of proteinaceous molecules such as but not limited to SOCS proteins and proteinaceous molecules associated therewith. The present invention provides a mechanism for modulating cytokine or cytokine-like molecule signalling by modulating the degradation of activated signal transduction molecules or their negative regulators, i.e. the SOCS proteins.