The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2006
Filed:
Oct. 16, 2001
Anthony Holder, London, GB;
Berry Birdsall, London, GB;
James Feeney, London, GB;
William Morgan, London, GB;
Shabih Syed, London, GB;
Chairat Uthaipibull, Bangkok, TH;
Anthony Holder, London, GB;
Berry Birdsall, London, GB;
James Feeney, London, GB;
William Morgan, London, GB;
Shabih Syed, London, GB;
Chairat Uthaipibull, Bangkok, TH;
Medical Research Council, London, GB;
Abstract
A non-naturally occurring variant of a C-terminal fragment of amerozoite surface protein-1 (MSP-1) wherein said variant has (i) a reduced affinity, compared with a naturally occurringMSP-1, for at least one first antibody capable of blocking the binding of a second antibody, which second antibody inhibits the proteolytic cleavage ofMSP-1and (ii) substantially the same affinity for at least one third antibody compared with said naturally occurringMSP-1. which third antibody inhibits the proteolytic cleavage ofMSP-1is provided for use in an anti-malarial vaccine.