The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2006

Filed:

Feb. 10, 2004
Applicants:

Donald B Axworthy, Brier, WA (US);

Louis J Theodore, Lynnwood, WA (US);

Linda M Gustavson, Guilford, CT (US);

John M Reno, Brier, WA (US);

Inventors:

Donald B Axworthy, Brier, WA (US);

Louis J Theodore, Lynnwood, WA (US);

Linda M Gustavson, Guilford, CT (US);

John M Reno, Brier, WA (US);

Assignee:

Aletheon Pharmaceuticals, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07D 257/02 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.


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