The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2006
Filed:
Oct. 03, 2001
John A. T. Young, Madison, WI (US);
Kenneth a Bradley, Madison, WI (US);
R. John Collier, Wellesley, MA (US);
Jeremy S. Mogridge, Toronto, CA;
John A. T. Young, Madison, WI (US);
Kenneth A Bradley, Madison, WI (US);
R. John Collier, Wellesley, MA (US);
Jeremy S. Mogridge, Toronto, CA;
Wisconsin Alumni Research Foundation, Madison, WI (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention relates to mammalian anthrax toxin receptor polypeptides and polynucleotides encoding same as well as related polypeptides and polynucleotides, vectors containing the polynucleotides and polypeptides, host cells containing related polynucleotide molecules, and cells displaying no anthrax toxin receptor on an exterior surface of the cells-minus cell lines and animals. The present invention also relates to methods for identifying molecules that bind the anthrax toxin receptor and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.