The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2006

Filed:

Mar. 02, 2001
Applicants:

Dana Litmanovitz, Sunnyvale, CA (US);

Barbara J. F. Laidlaw, San Jose, CA (US);

Inventors:

Dana Litmanovitz, Sunnyvale, CA (US);

Barbara J. F. Laidlaw, San Jose, CA (US);

Assignee:

Durect Corporation, Cupertino, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); C07D 211/36 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides high-concentration formulations of opioids such as fentanyl or fentanyl congeners. The formulation of the invention comprises fentanyl or a fentanyl congener in concentrations significantly in excess of conventional formulations, e.g., on the order about 2-fold to about 10,000-fold greater than conventional formulations, e.g., currently commercially available formulations. These formulations are particularly useful for long-term delivery to a subject suffering from pain. The invention further provides drug delivery devices comprising the high-concentration opioid formulations, and further provides methods of alleviating pain in a subject, comprising administering the high-concentration formulations to a subject in need thereof.


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