The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2006
Filed:
Oct. 31, 2003
David M. Armistead, Sudbury, MA (US);
Jean E. Bemis, Arlington, MA (US);
John L. Buchanan, Brookline, MA (US);
Lucian V. Dipietro, Gloucester, MA (US);
Daniel Elbaum, Newton, MA (US);
Stephanie D. Geuns-meyer, Medford, MA (US);
Gregory J. Habgood, Merrimack, MA (US);
Joseph L. Kim, Wayland, MA (US);
Teresa L. Marshall, Stow, MA (US);
Perry M. Novak, Milford, MA (US);
Joseph J. Nunes, Andover, MA (US);
Vinod F. Patel, Acton, MA (US);
Leticia M. Toledo-sherman, Venice, CA (US);
Xiaotian Zhu, Watertown, MA (US);
David M. Armistead, Sudbury, MA (US);
Jean E. Bemis, Arlington, MA (US);
John L. Buchanan, Brookline, MA (US);
Lucian V. DiPietro, Gloucester, MA (US);
Daniel Elbaum, Newton, MA (US);
Stephanie D. Geuns-Meyer, Medford, MA (US);
Gregory J. Habgood, Merrimack, MA (US);
Joseph L. Kim, Wayland, MA (US);
Teresa L. Marshall, Stow, MA (US);
Perry M. Novak, Milford, MA (US);
Joseph J. Nunes, Andover, MA (US);
Vinod F. Patel, Acton, MA (US);
Leticia M. Toledo-Sherman, Venice, CA (US);
Xiaotian Zhu, Watertown, MA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The invention relates to inhibitors of enzymes that bind to ATP or GTP and/or catalyze phosphoryl transfer, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making phosphoryl transferase inhibitor compounds, methods of inhibiting phosphoryl transferase activity, and methods for treating disease or disease symptoms.