The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2006
Filed:
Dec. 11, 2000
Roy C. Levitt, Plymouth Meeting, PA (US);
Nicholas C. Nicolaides, Plymouth Meeting, PA (US);
William A. Kinney, Plymouth Meeting, PA (US);
Steve Jones, Plymouth Meeting, PA (US);
Roy C. Levitt, Plymouth Meeting, PA (US);
Nicholas C. Nicolaides, Plymouth Meeting, PA (US);
William A. Kinney, Plymouth Meeting, PA (US);
Steve Jones, Plymouth Meeting, PA (US);
Genaera Corporation, Plymouth Meeting, PA (US);
Abstract
This invention relates to methods for treating asthma or allergy in a mammal by administering a 3-aminosteroid compound to a mammal in need thereof. The 3-aminosteroid compound being capable of down regulating the IL-9 pathway and alleviating asthmatic responses to allergen. Exemplary 3-aminosteroid compounds used in the methods of the invention include compounds having the chemical formula (I), wherein X, R, R, R, and Rgroups are as defined herein. The invention also relates to certain novel compounds of formula (I). Moreover, the invention also provides methods for identifying an immunomodulatory 3-aminosteroid compound.