The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2006

Filed:

May. 11, 1999
Applicants:

Nigel S. Dunn-coleman, Los Gatos, CA (US);

Anthony A. Gatenby, Wilmington, DE (US);

Fernando Valle, Burlingame, CA (US);

Inventors:

Nigel S. Dunn-Coleman, Los Gatos, CA (US);

Anthony A. Gatenby, Wilmington, DE (US);

Fernando Valle, Burlingame, CA (US);

Assignees:

E. I. du Pont de Nemours and Company, Wilmington, DE (US);

Genencor International, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

Recombinant organisms are provided comprising genes encoding aquacobalamin reductase, cob(II)alamin reductase, cob(I)alamin adenosyltransferase, glycerol dehydratase and 1,3-propanediol oxidoreductase activities useful for the production of 1,3-propanediol from a variety of carbon substrates. More specifically the following nucleotide sequences are provided: btuR, encoding thecob(I)alamin adenosyltransferase enzyme; cobA, encoding thecob(I)alamin adenosyltransferase enzyme; cobO, encoding thecob(I)alamin adenosyltransferase enzyme; dhaB1, encoding the α subunit of theglycerol dehydratase enzyme; dhaB2, encoding the β subunit of theglycerol dehydratase enzyme; dhaB3, encoding the γ subunit of theglycerol dehydratase enzyme; dhaT, encodingoxidoreductase enzyme; the yciK gene isolated from; the glucose isomerase promoter sequence from; and the N-terminal amino acid sequence for cob(II)alamin reductase from


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