The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2006
Filed:
Feb. 23, 2001
William C. Fanslow, Iii, Seattle, WA (US);
Douglas P. Cerretti, Seattle, WA (US);
Kurt M. Poindexter, Seattle, WA (US);
Roy A. Black, Seattle, WA (US);
William C. Fanslow, III, Seattle, WA (US);
Douglas P. Cerretti, Seattle, WA (US);
Kurt M. Poindexter, Seattle, WA (US);
Roy A. Black, Seattle, WA (US);
Immunex Corporation, Seattle, WA (US);
Abstract
The present invention provides methods and compositions for inhibiting the biological activity of integrins, for inhibiting endothelial cell migration. and for inhibiting angiogenesis. In particular, the invention provides compositions comprising ADAM disintegrin domains and methods for using said compositions. In preferred embodiments the methods and compositions of the invention are used to inhibit angiogenesis and to treat diseases or conditions mediated by angiogenesis.