The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2006

Filed:

May. 02, 2001
Applicants:

Noritaka Kitazawa, Ibaraki, JP;

Kohshi Ueno, Ibaraki, JP;

Keiko Takahashi, Ibaraki, JP;

Teiji Kimura, Ibaraki, JP;

Atsushi Sasaki, Ibaraki, JP;

Koki Kawano, Ibaraki, JP;

Tadashi Okabe, Ibaraki, JP;

Makoto Komatsu, Ibaraki, JP;

Manabu Matsunaga, Ibaraki, JP;

Atsuhiko Kubota, Ibaraki, JP;

Inventors:

Noritaka Kitazawa, Ibaraki, JP;

Kohshi Ueno, Ibaraki, JP;

Keiko Takahashi, Ibaraki, JP;

Teiji Kimura, Ibaraki, JP;

Atsushi Sasaki, Ibaraki, JP;

Koki Kawano, Ibaraki, JP;

Tadashi Okabe, Ibaraki, JP;

Makoto Komatsu, Ibaraki, JP;

Manabu Matsunaga, Ibaraki, JP;

Atsuhiko Kubota, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/435 (2006.01); A61K 31/55 (2006.01); C07D 211/68 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A novel compound of the formula:wherein A, B, C, D, T, Y, and Z represent each methine or nitrogen; RR, R, R, and Rrepresent each a substituent; n represents 0 or an integer of 1 to 3; m represents 0 or an integer of 1 to 6; and p represents an integer of 1 to 3; and pharmacologically acceptable salts thereof. The compound has a serotonin antagonism and is clinically useful as medicament, in particular, for treating, ameliorating and preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.


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