The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7071176 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 04, 2006

Filed:

Dec. 01, 2003
Applicants:

Faith M. Uckun, White Bear Lake, MN (US);

Rakesh Vig, Little Canada, MN (US);

Inventors:

Faith M. Uckun, White Bear Lake, MN (US);

Rakesh Vig, Little Canada, MN (US);

Assignee:

Parker Hughes Institute, Roseville, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/685 (2006.01); C07F 9/6512 (2006.01);
U.S. Cl.
CPC ...
Abstract

Aryl phosphate derivatives of d4T with para-bromo substitution on the aryl group show markedly increased potency as anti-HIV agents without undesirable levels of cytotoxic activity. In particular, these derivatives are potent inhibitors of HIV reverse transcriptase. In a preferred aspect of the present invention, the phosphorus of the aryl phosphate group is further substituted with an amino acid residue that may be esterified or substituted, such as a methoxy alaninyl group.


Find Patent Forward Citations

Uckun, Faith. (2006). Aryl phosphate derivatives of azt having anti-hiv activity (U.S. Patent No. 7071176). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7071176

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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