The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2006

Filed:

Apr. 09, 2003
Applicants:

A. Sampath Narayanan, Seattle, WA (US);

Sandu Pitaru, Ramat Gan, 52290, Tel Aviv, IL;

Roy C. Page, Seattle, WA (US);

Anthony C. Allison, Belmont, CA (US);

Inventors:

A. Sampath Narayanan, Seattle, WA (US);

Sandu Pitaru, Ramat Gan, 52290, Tel Aviv, IL;

Roy C. Page, Seattle, WA (US);

Anthony C. Allison, Belmont, CA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); A61K 38/12 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method is described for inducing the formation of cementum and a periodontal ligament between a dental implant and bone by administering cementum attachment protein (CAP) together with a calcineurin inhibitor such as cyclosporin A (CSA). Also contemplated is an implant kit comprising a titanium or other biologically inert dental or orthopedic implant and a coating of CAP and a calcineurin inhibitor such as CSA. Furthermore, application of CAP and CSA to dental root surfaces can be used to induce the regeneration of a periodontal ligament during treatment for periodontal disease. A similar method for reattaching a fibrous structure, such as a tendon, ligament or joint capsule, to bone is described.


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