The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2006

Filed:

Feb. 07, 2001
Applicants:

Rebecca Chinery, Nashville, TN (US);

R. Daniel Beauchamp, Nashville, TN (US);

Robert J. Coffey, Woodside, CA (US);

Russell M. Medford, Atlanta, GA (US);

Brian E. Wadzinski, Nashville, TN (US);

Inventors:

Rebecca Chinery, Nashville, TN (US);

R. Daniel Beauchamp, Nashville, TN (US);

Robert J. Coffey, Woodside, CA (US);

Russell M. Medford, Atlanta, GA (US);

Brian E. Wadzinski, Nashville, TN (US);

Assignee:

Atherogenics, Inc., Norcross, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 31/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method to enhance the cytotoxic activity of an antineoplastic drug comprising administering an effective amount of the antineoplastic drug to a host exhibiting abnormal cell proliferation in combination with an effective cytotoxicity-increasing amount of an antioxidant. The invention also includes a method to decrease the toxicity to an antineoplastic agent or increase the therapeutic index of an antineoplastic agent administered for the treatment of a solid growth of abnormally proliferating cells, comprising administering an antioxidant prior to, with, or following the antineoplastic treatment.


Find Patent Forward Citations

Loading…