The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2006
Filed:
May. 22, 2002
Yuji Imai, Ashiya, JP;
Hiroyuki Akatsuka, Kokubunji, JP;
Eri Kawai, Otsu, JP;
Kenji Omori, Saitama, JP;
Noriyuki Yanaka, Higashihiroshima, JP;
Naoki Sakurai, Mitaka, JP;
Yuji Imai, Ashiya, JP;
Hiroyuki Akatsuka, Kokubunji, JP;
Eri Kawai, Otsu, JP;
Kenji Omori, Saitama, JP;
Noriyuki Yanaka, Higashihiroshima, JP;
Naoki Sakurai, Mitaka, JP;
Tanabe Seiyaku Co., Ltd., Osaka, JP;
Abstract
The present invention is directed to a novel method of detecting a function or activity of a polypeptide which is related to bone metabolism, in particular, differentiation (maturation) of osteoblast or morphological change (retraction), specifically relating to a polypeptide which comprises an amino acid sequence shown by SEQ ID NO: 2 or SEQ ID NO: 4, an amino acid sequence in which one or several amino acids are deleted, substituted or added in the amino acid sequence shown by SEQ ID NO: 2 or SEQ ID NO: 4, or a polypeptide encoded by a nucleic acid which is capable of hybridizing under stringent condition with a nucleic acid comprising a nucleotide sequence shown by SEQ ID NO: 1 or SEQ ID NO: 3, or a complement sequence thereof.