The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2006

Filed:

Jan. 24, 2003
Applicant:

Rino Rappuoli, Quercegrossa, IT;

Inventor:

Rino Rappuoli, Quercegrossa, IT;

Assignee:

Chiron SRL, Siena, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 38/00 (2006.01); A61K 39/095 (2006.01); A61K 39/02 (2006.01); A61K 39/145 (2006.01); A61K 39/106 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); A01N 37/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

A non-toxic mucosal adjuvant is provided which may be admixed with further antigens to provide a vaccine administrable to mucosal surfaces in organisms including man. Preferably, the non-toxic mucosal adjuvant is a detoxified mutant of a bacterial ADP-ribosylating toxin, optionally comprising one or more amino acid additions, deletions or substitutions.


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