The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2006

Filed:

Dec. 20, 2002
Applicants:

Giampiero Morini, Padua, IT;

Fabrizio Piemontesi, Ferrara, IT;

Antonio Cristofori, S. M. Maddalena, IT;

Stefania Milani, Romano d'Ezzelino, IT;

Inventors:

Giampiero Morini, Padua, IT;

Fabrizio Piemontesi, Ferrara, IT;

Antonio Cristofori, S. M. Maddalena, IT;

Stefania Milani, Romano d'Ezzelino, IT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

Process for modifying the relative ratios of the components of a liquid starting mixture of specific diastereoisomers, containing at least two asymmetric carbon atoms comprising contacting said liquid mixture with a Lewis acid compound capable of co-ordinating a compound having at least two Lewis basic functionalities and subjecting the resulting mixture to conditions such that a reaction product, having a molar ratio between its diastereoisomeric components different from the corresponding molar ratio in the said liquid starting mixture, becomes separated from the said liquid mixture, said process being carried out using an amount of said Lewis acid not enough to co-ordinate the total amount of the diastereoisomeric components of the liquid starting mixture. This method shows an excellent balance of efficiency and easiness of procedure that cannot be reached with the physical methods of diastereoisomers separation known in the art.


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