The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2006

Filed:

Jan. 19, 2005
Applicants:

Marc Nazare, Eppstein, DE;

David William Will, Kriftel, DE;

Anuschirwan Peyman, Kelkheim, DE;

Hans Matter, Langenselbold, DE;

Gerhard Zoller, Schoeneck, DE;

Uwe Gerlach, Hattersheim, DE;

Inventors:

Marc Nazare, Eppstein, DE;

David William Will, Kriftel, DE;

Anuschirwan Peyman, Kelkheim, DE;

Hans Matter, Langenselbold, DE;

Gerhard Zoller, Schoeneck, DE;

Uwe Gerlach, Hattersheim, DE;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt Ammain, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds comprising the following formula:R-Q-X-Q'-W-U-V-G-M  (I)These compounds are useful as pharmacologically active compounds. They exhibit an antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders such as thromboembolic diseases or restenoses. These compounds are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can generally be used to treat, prevent, or cure conditions in which an undesired activity of factor Xa and/or factor VIIa is present, or where inhibition of factor Xa and/or factor VIIa is intended. The invention further relates to processes for the preparation of these compounds, methods of their use (e.g., as active ingredients in pharmaceuticals), and pharmaceutical preparations comprising them.


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