The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2006

Filed:

Dec. 16, 2002
Applicants:

Cornelis J. Leenhouts, Haren, NL;

Ranjan Ramasamy, Colombo, LK;

Anton Steen, Groningen, NL;

Jan Kok, Groningen, NL;

Girbe Buist, Sappemeer, NL;

Oscar P. Kuipers, Groningen, NL;

Inventors:

Cornelis J. Leenhouts, Haren, NL;

Ranjan Ramasamy, Colombo, LK;

Anton Steen, Groningen, NL;

Jan Kok, Groningen, NL;

Girbe Buist, Sappemeer, NL;

Oscar P. Kuipers, Groningen, NL;

Assignee:

Applied Nanosystems B.V., Groningen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 39/02 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); C12N 1/00 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating the cell-wall material with a solution capable of removing a cell-wall component such as a protein, lipoteichoic acid or carbohydrate from the cell-wall material and contacting the proteinaceous substance with the cell-wall material.


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