The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7067633 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 27, 2006

Filed:

Feb. 26, 2004
Applicants:

Rakesh Kumar, Houston, TX (US);

Ratna Vadlamudi, Houston, TX (US);

Inventors:

Rakesh Kumar, Houston, TX (US);

Ratna Vadlamudi, Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of modulating macropinocytosis in cells of a target cell population by modulating the binding of Pak1 to DLC1/PIN are disclosed. In addition, the invention provides for methods of screening for modulators of macropinocytosis that involve determining whether a candidate substance inhibits or promotes the binding of Pak1 to DLC1/PIN. Also disclosed are methods of reducing cell proliferation in a target cell population, methods of inhibiting growth and survival of a cancer cell, methods of inhibiting the invasiveness of a cancer cell, and methods of treating viral infection using an agent that modifies the binding of Pak1 to DLC1/PIN.


Find Patent Forward Citations

Kumar, Rakesh. (2006). Targeting cellular entry, cell survival, and pathogenicity by dynein light chain 1/pin in human cells (U.S. Patent No. 7067633). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7067633

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