The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Dec. 27, 2002
Markus Isler, Allschwil, CH;
Thomas Giller, Wintersingen, CH;
Günter Schwalm, Binningen, CH;
Matthias Steger, Zürich, CH;
Kurt Hilpert, Hofstetten, CH;
Oliver Valdenaire, Allschwil, CH;
Volker Breu, Schliengen, DE;
Markus Isler, Allschwil, CH;
Thomas Giller, Wintersingen, CH;
Günter Schwalm, Binningen, CH;
Matthias Steger, Zürich, CH;
Kurt Hilpert, Hofstetten, CH;
Oliver Valdenaire, Allschwil, CH;
Volker Breu, Schliengen, DE;
Actelion Pharmaceuticals AG, Allschwil, CH;
Abstract
Pyrrolidone carboxamides of formula (I) where R=a group of formula (a) or (b), R=phenyl, heteroalkyl, aryloxy, alkoxy, alkanoyl or —NRRand R, X, R, R, Rand Rhave the meanings given in the description and the claims, pharmaceutically applicable acid addition salts with basic compounds of formula (I), pharmaceutically applicable salts of acid compounds of formula (I) with bases, pharmaceutically applicable esters of hydroxy- or carboxy-group containing compounds of formula (I) and hydrates and solvates thereof, inhibit the interaction of neuropeptide Y (NPY) with one of the neuropeptide receptor subtypes (NPY-Y5) and are particularly suitable for the prevention and treatment of arthritis, diabetes and especially eating disorders and obesity. The above can be produced by known methods and converted into a galenic dosage form.