The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2006

Filed:

Apr. 16, 2004
Applicants:

Nobert Hofgen, Ottendorf-Okrilla, DE;

Hildegard Kuss, Dresden, DE;

Karin Steinike, Radebeul, DE;

Ute Egerland, Radebeul, DE;

Chris Rundfeldt, Coswig, DE;

Inventors:

Nobert Hofgen, Ottendorf-Okrilla, DE;

Hildegard Kuss, Dresden, DE;

Karin Steinike, Radebeul, DE;

Ute Egerland, Radebeul, DE;

Chris Rundfeldt, Coswig, DE;

Assignee:

Elbion AG, Radebeul, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to substituted 4-, 6- or 7-hydroxyindoles with N-oxide groups, process for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.


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