The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7067506 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 27, 2006

Filed:

Mar. 01, 2002
Applicants:

Kathleen S. Keegan, Mercer Island, WA (US);

Edward A. Kesicki, Bothell, WA (US);

John Joseph Gaudino, Longmont, CO (US);

Adam Wade Cook, Longmont, CO (US);

Scott Douglas Cowen, Longmont, CO (US);

Laurence Edward Burgess, Boulder, CO (US);

Inventors:

Kathleen S. Keegan, Mercer Island, WA (US);

Edward A. Kesicki, Bothell, WA (US);

John Joseph Gaudino, Longmont, CO (US);

Adam Wade Cook, Longmont, CO (US);

Scott Douglas Cowen, Longmont, CO (US);

Laurence Edward Burgess, Boulder, CO (US);

Assignee:

ICOS Corporation, Bothwell, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01); C07D 241/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed.


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